Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101778 | 0.87 | TYK2 (0.40) | TYK2 | |
| SCHEMBL30392945 | 0.87 | TYK2 (0.40) | TYK2 | |
| SCHEMBL31161422 | 0.73 | TYK2 (0.33) | TYK2 | |
| SCHEMBL26099068 | 0.70 | TYK2 (0.44) | TYK2 | |
| SCHEMBL30392439 | 0.67 | TYK2 (0.43) | TYK2 | |
| SCHEMBL26103080 | 0.67 | TYK2 (0.43) | TYK2 | |
| SCHEMBL30392771 | 0.67 | TYK2 (0.43) | TYK2 | |
| SCHEMBL26098254 | 0.67 | TYK2 (0.43) | TYK2 | |
| SCHEMBL26100108 | 0.67 | TYK2 (0.41) | TYK2 | |
| SCHEMBL30392624 | 0.66 | TYK2 (0.41) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |