Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | FLT1 | P17948 | 3/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098888 | 1.00 | CSF1R (0.43) | CSF1RMAPK7AXLFLT3MERTK | |
| SCHEMBL26102835 | 0.87 | KIT (0.43) | MAPK7KDREGFRFLT1FLT4 | |
| SCHEMBL26099737 | 0.86 | BRAF (0.46) | MAPK7KDRFLT1KITBRAF | |
| SCHEMBL30394282 | 0.86 | KIT (0.43) | MAPK7KDREGFRFLT1FLT4 | |
| SCHEMBL26098943 | 0.85 | FLT4 (0.43) | MAPK7FLT3KDREGFRALOX5 | |
| SCHEMBL26102072 | 0.85 | FLT4 (0.43) | MAPK7FLT3KDREGFRALOX5 | |
| SCHEMBL26101209 | 0.84 | KIT (0.48) | MAPK7FLT3KDREGFRFLT1 | |
| SCHEMBL26102268 | 0.84 | KDR (0.53) | FLT3KDREGFRFLT1FLT4 | |
| SCHEMBL26101857 | 0.84 | KIT (0.42) | KDREGFRKITBRAF | |
| SCHEMBL26102229 | 0.84 | EGFR (0.44) | KDREGFRKITERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |