Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 11/20 | 0.46 |
| ▸ | RAF1 | P04049 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.45 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101857 | 0.97 | KIT (0.42) | BRAFRAF1KDRKIT | |
| SCHEMBL30394282 | 0.92 | KIT (0.43) | BRAFRAF1KDRKITMAPK7 | |
| SCHEMBL26102835 | 0.92 | KIT (0.43) | BRAFRAF1KDRKITMAPK7 | |
| SCHEMBL26100822 | 0.92 | BRAF (0.43) | BRAFRAF1KDRKITAURKB | |
| SCHEMBL26101918 | 0.89 | MCHR1 (0.48) | KDRKIT | |
| SCHEMBL26102229 | 0.88 | EGFR (0.44) | KDRKITAURKB | |
| SCHEMBL26100658 | 0.88 | EGFR (0.45) | BRAFRAF1KDRKITMAPK7 | |
| SCHEMBL26102268 | 0.87 | KDR (0.53) | KDRKITAURKBFLT1 | |
| SCHEMBL26098888 | 0.86 | CSF1R (0.43) | BRAFKDRKITMAPK7FLT1 | |
| SCHEMBL26101171 | 0.86 | CSF1R (0.43) | BRAFKDRKITMAPK7FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |