Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393934 | 0.93 | HSD17B2 (0.53) | HSD17B2PDGFRBPDGFRAAURKBTP53 | |
| SCHEMBL29238242 | 0.88 | AURKB (0.42) | HSD17B2AURKBAURKAKDM4EPDE10A | |
| SCHEMBL26101189 | 0.85 | PDGFRB (0.50) | PDGFRBPDGFRATP53NPC1MAPT | |
| Trifluoroacetic Acid SCHEMBL26099390 | 0.80 | ABCG2 (0.49) | PDGFRBPDGFRAAURKBAURKAALDH1A1 | |
| SCHEMBL26099045 | 0.80 | PDGFRB (0.51) | PDGFRBPDGFRANPC1KDM4EHPGD | |
| SCHEMBL4725216 | 0.75 | EGFR (0.58) | PDGFRBPDGFRAAURKBAURKAEGFR | |
| SCHEMBL26101625 | 0.74 | KDR (0.65) | AURKBAURKAEGFRKDR | |
| SCHEMBL31137829 | 0.73 | KDR (0.57) | PDGFRBAURKBAURKAEGFRKDR | |
| SCHEMBL26098307 | 0.73 | KDR (0.57) | PDGFRBAURKBAURKAEGFRKDR | |
| SCHEMBL4729758 | 0.72 | EGFR (0.48) | PDGFRBPDGFRAAURKBAURKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |