Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26101191 | 0.85 | HSD17B2 (0.46) | PDGFRBPDGFRAPDE10AKITMEN1 | |
| SCHEMBL30393934 | 0.83 | HSD17B2 (0.53) | PDGFRBPDGFRAKITMEN1TP53 | |
| SCHEMBL26099045 | 0.82 | PDGFRB (0.51) | PDGFRBPDGFRAKITNPC1HTT | |
| SCHEMBL26099389 | 0.80 | ABCG2 (0.52) | PDGFRBPDGFRAPDE10AKITKDR | |
| SCHEMBL29238242 | 0.80 | AURKB (0.42) | PDE10AKITKDRENPP1CAMKK1 | |
| SCHEMBL31137829 | 0.77 | KDR (0.57) | PDGFRBKITKDREGFR | |
| SCHEMBL26098307 | 0.77 | KDR (0.57) | PDGFRBKITKDREGFR | |
| SCHEMBL5569427 | 0.74 | KIT (0.58) | PDE10AKITKDRENPP1EGFR | |
| SCHEMBL6662871 | 0.72 | KDR (0.77) | KDREGFR | |
| SCHEMBL6180664 | 0.70 | KIT (0.61) | PDGFRBPDGFRAKITKDRENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |