Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.54 |
| ▸ | KIT | P10721 | 4/20 | 0.52 |
| ▸ | KDR | P35968 | 5/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.51 |
| ▸ | AURKA | O14965 | 4/20 | 0.50 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | TTK | P33981 | 1/20 | 0.50 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.50 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102268 | 0.93 | KDR (0.53) | EGFRKITKDRAURKAAURKB | |
| SCHEMBL26101209 | 0.91 | KIT (0.48) | EGFRKITKDRAURKAAURKB | |
| SCHEMBL26101200 | 0.89 | EGFR (0.49) | EGFRKITKDRBRAFAURKA | |
| SCHEMBL26098355 | 0.89 | TLR9 (0.48) | EGFRKITKDRAURKAAURKB | |
| SCHEMBL26099804 | 0.89 | TLR9 (0.48) | EGFRKITKDRAURKAAURKB | |
| SCHEMBL26103399 | 0.88 | KDR (0.44) | EGFRKITKDRBRAFAURKA | |
| SCHEMBL26101784 | 0.88 | KDR (0.43) | EGFRKITKDRBRAFAURKA | |
| SCHEMBL26133412 | 0.88 | FLT1 (0.43) | EGFRKITKDRAURKAAURKB | |
| SCHEMBL26100028 | 0.88 | FLT1 (0.43) | EGFRKITKDRAURKAAURKB | |
| SCHEMBL26101223 | 0.87 | KDR (0.44) | EGFRKITKDRBRAFAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |