Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | FLT1 | P17948 | 3/20 | 0.43 |
| ▸ | FLT4 | P35916 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.41 |
| ▸ | AURKA | O14965 | 3/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101223 | 0.91 | KDR (0.44) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26101444 | 0.91 | KDR (0.44) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26099803 | 0.90 | KDR (0.43) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26101200 | 0.90 | EGFR (0.49) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26100971 | 0.90 | KDR (0.43) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26102268 | 0.90 | KDR (0.53) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26101243 | 0.88 | EGFR (0.54) | KDREGFRAURKAAURKBRET | |
| SCHEMBL26101209 | 0.87 | KIT (0.48) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26100028 | 0.87 | FLT1 (0.43) | KDRFLT1FLT4EGFRAURKA | |
| SCHEMBL26133412 | 0.87 | FLT1 (0.43) | KDRFLT1FLT4EGFRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |