Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.51 |
| ▸ | FLT1 | P17948 | 4/20 | 0.51 |
| ▸ | FLT4 | P35916 | 4/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.51 |
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 4/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100102 | 0.89 | EGFR (0.62) | KDREGFRKIT | |
| SCHEMBL26101812 | 0.87 | EGFR (0.52) | KDREGFRKITPDGFRBPDGFRA | |
| SCHEMBL30395061 | 0.86 | KIT (0.54) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26102118 | 0.86 | KIT (0.54) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26101038 | 0.85 | RAF1 (0.48) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099433 | 0.85 | EGFR (0.52) | KDREGFRKITPDGFRBFLT3 | |
| SCHEMBL30394281 | 0.85 | EGFR (0.52) | KDREGFRKITPDGFRBFLT3 | |
| SCHEMBL30394178 | 0.84 | KDR (0.48) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL30891790 | 0.84 | KDR (0.46) | KDREGFRFGFR1FLT1FLT4 | |
| SCHEMBL26536043 | 0.84 | KDR (0.46) | KDREGFRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |