Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.62 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | KIT | P10721 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101812 | 0.91 | EGFR (0.52) | EGFRKDRKIT | |
| SCHEMBL26099433 | 0.91 | EGFR (0.52) | EGFRKDRKIT | |
| SCHEMBL30394281 | 0.91 | EGFR (0.52) | EGFRKDRKIT | |
| SCHEMBL26101262 | 0.89 | KDR (0.51) | EGFRKDRKIT | |
| SCHEMBL31137783 | 0.85 | EGFR (0.54) | EGFRKDRKIT | |
| SCHEMBL26535296 | 0.85 | EGFR (0.54) | EGFRKDRKIT | |
| SCHEMBL29238264 | 0.84 | KDR (0.53) | EGFRKDRKIT | |
| SCHEMBL30394389 | 0.84 | KDR (0.53) | EGFRKDRKIT | |
| SCHEMBL30393893 | 0.84 | EGFR (0.64) | EGFRKDRKIT | |
| SCHEMBL26100098 | 0.84 | EGFR (0.56) | EGFRKDRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |