Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.51 |
| ▸ | KDR | P35968 | 16/20 | 0.51 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | KIF5B | P33176 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101510 | 0.89 | KDR (0.53) | EGFRKDRCSF1RFGFR1FLT1 | |
| SCHEMBL26098803 | 0.84 | KDR (0.49) | EGFRKDRCSF1RFGFR1FLT1 | |
| SCHEMBL26103247 | 0.84 | KDR (0.48) | EGFRKDRFLT4RETKIF5B | |
| SCHEMBL26101960 | 0.83 | KDR (0.54) | EGFRKDRFLT4RETKIF5B | |
| SCHEMBL26102383 | 0.83 | KDR (0.48) | EGFRKDRCSF1RFLT4RET | |
| SCHEMBL26099266 | 0.82 | KDR (0.59) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL30891764 | 0.82 | KDR (0.59) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26101653 | 0.82 | KDR (0.51) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26101506 | 0.82 | KDR (0.53) | EGFRKDRFLT4RETKIF5B | |
| SCHEMBL30891810 | 0.82 | KDR (0.55) | EGFRKDRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |