Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.49 |
| ▸ | KDR | P35968 | 8/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | KIF5B | P33176 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.46 |
| ▸ | FLT1 | P17948 | 6/20 | 0.46 |
| ▸ | FLT4 | P35916 | 6/20 | 0.46 |
| ▸ | KIT | P10721 | 5/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | CIT | O14578 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | STK10 | O94804 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394062 | 1.00 | EGFR (0.49) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL26102560 | 0.93 | EGFR (0.48) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL30891778 | 0.93 | MAPK7 (0.45) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL26099862 | 0.93 | MAPK7 (0.45) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL26100162 | 0.93 | MAPK7 (0.48) | EGFRKDRKITERBB2EPHA2 | |
| SCHEMBL26100179 | 0.92 | KIT (0.44) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL26103463 | 0.90 | MAPK7 (0.44) | EGFRKDRFLT1KITERBB2 | |
| SCHEMBL26099799 | 0.90 | KDR (0.46) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26100035 | 0.90 | KDR (0.46) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26101421 | 0.88 | MAPK7 (0.43) | EGFRKDRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |