Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | FLT1 | P17948 | 4/20 | 0.40 |
| ▸ | FLT4 | P35916 | 4/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | KIF5B | P33176 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26103289 | 0.93 | KIT (0.43) | KITEGFRAURKBKDRFLT1 | |
| SCHEMBL26099300 | 0.92 | KDR (0.44) | KITMAPK7SLC2A1EGFRKDR | |
| SCHEMBL26099862 | 0.92 | MAPK7 (0.45) | KITMAPK7SLC2A1EGFRAURKB | |
| SCHEMBL30891778 | 0.92 | MAPK7 (0.45) | KITMAPK7SLC2A1EGFRAURKB | |
| SCHEMBL30394062 | 0.92 | EGFR (0.49) | KITMAPK7SLC2A1EGFRAURKB | |
| SCHEMBL26101933 | 0.92 | EGFR (0.49) | KITMAPK7SLC2A1EGFRAURKB | |
| SCHEMBL26103463 | 0.90 | MAPK7 (0.44) | KITMAPK7SLC2A1EGFRKDR | |
| SCHEMBL26100162 | 0.89 | MAPK7 (0.48) | KITMAPK7SLC2A1EGFRKDR | |
| SCHEMBL26101209 | 0.87 | KIT (0.48) | KITMAPK7EGFRAURKBAURKA | |
| SCHEMBL26100035 | 0.87 | KDR (0.46) | KITMAPK7SLC2A1EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |