Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 10/20 | 0.52 |
| ▸ | EGFR | P00533 | 7/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 4/20 | 0.44 |
| ▸ | FLT4 | P35916 | 4/20 | 0.44 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101780 | 0.89 | KIT (0.48) | KITEGFRKDR | |
| SCHEMBL26102114 | 0.87 | KIT (0.51) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL26098297 | 0.83 | EGFR (0.51) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099903 | 0.82 | EGFR (0.45) | KITEGFRKDRIRAK4 | |
| SCHEMBL26100035 | 0.81 | KDR (0.46) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099799 | 0.81 | KDR (0.46) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099840 | 0.80 | EGFR (0.43) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL26102118 | 0.80 | KIT (0.54) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL30395061 | 0.80 | KIT (0.54) | KITEGFRFGFR1FLT1FLT4 | |
| SCHEMBL26099698 | 0.79 | KDR (0.47) | KITEGFRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |