Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.51 |
| ▸ | KDR | P35968 | 7/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.51 |
| ▸ | FLT1 | P17948 | 5/20 | 0.51 |
| ▸ | FLT4 | P35916 | 5/20 | 0.51 |
| ▸ | KIT | P10721 | 5/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100098 | 0.89 | EGFR (0.56) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26101805 | 0.87 | KIT (0.46) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26102144 | 0.86 | EGFR (0.46) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26099698 | 0.85 | KDR (0.47) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26099430 | 0.85 | KIT (0.48) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26102114 | 0.85 | KIT (0.51) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26101262 | 0.84 | KDR (0.51) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26101865 | 0.83 | KDR (0.45) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL26102116 | 0.83 | KIT (0.52) | EGFRKDRFGFR1FLT1FLT4 | |
| SCHEMBL30891790 | 0.83 | KDR (0.46) | EGFRKDRFGFR1FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |