Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | CLK3 | P49761 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30917341 | 1.00 | NPC1 (0.74) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL27609695 | 0.98 | NPC1 (0.72) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL27609657 | 0.98 | NPC1 (0.72) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL8980158 | 0.86 | KDM4E (0.61) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL192332 | 0.85 | NPC1 (1.00) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| Hydrochloric Acid SCHEMBL4255724 | 0.84 | NPC1 (0.96) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL10347638 | 0.84 | NPC1 (0.96) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL4155826 | 0.84 | NPC1 (0.53) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL17679198 | 0.84 | NPC1 (0.53) | NPC1RAB9ATDP1KDM4EHKDC1 | |
| SCHEMBL8861663 | 0.84 | NPC1 (0.53) | NPC1RAB9ATDP1KDM4EHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834382-A | Preparation method of intrinsic antibacterial nylon based on end capping strategy | 湘潭大学 | 2024-10-25 | — | — | CN | claimed |
| EP-3652164-B1 | PHENYLACETAMIDES AS INHIBITORS OF ROCK | BRISTOL MYERS SQUIBB CO (US) | 2023-06-21 | — | — | EP | claimed |
| CN-111278817-B | Polycyclic compounds as farnesol X receptor modulators | 百时美施贵宝公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115850173-A | Naphthalimide compound and preparation method and application thereof | 中国人民解放军陆军防化学院 | 2023-03-28 | — | — | CN | claimed |
| CN-107686284-B | Composite material for caulking, repairing and waterproofing of concrete or inorganic plate | 佛山科学技术学院 | 2020-03-20 | — | — | CN | claimed |
| CN-107399944-B | A kind of flexible material modified portland cement encapsulation composite material | 佛山科学技术学院 | 2019-12-03 | — | — | CN | claimed |
| CN-107399918-B | A kind of Semi-rigid concrete composition | FOSHAN UNIVERSITY (CN) | 2019-10-29 | — | — | CN | claimed |
| CN-107686284-A | It is a kind of to be used for concrete or inorganic plate filleting, repairing, the composite of waterproof | 佛山科学技术学院 | 2018-02-13 | — | — | CN | claimed |
| CN-107399918-A | A kind of Semi-rigid concrete composition | 佛山科学技术学院 | 2017-11-28 | — | — | CN | claimed |
| CN-107399944-A | A kind of flexible material modified portland cement encapsulates composite | 佛山科学技术学院 | 2017-11-28 | — | — | CN | claimed |
| US-20130018043-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | BILOTTA JOSEPH A (US) | 2013-01-17 | — | — | US | claimed |
| EP-1102769-B1 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-04-16 | — | — | EP | claimed |
| CN-1324359-A | Tricyclic carboxamides | SMITHKLINE BEECHAM PLC (GB) | 2001-11-28 | — | — | CN | claimed |
| EP-1102769-A2 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2001-05-30 | — | — | EP | claimed |
| WO-2000008020-A2 | TRICYCLIC CARBOXAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-02-17 | — | — | WO | claimed |
| EP-0682663-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | PHARMACIA & UPJOHN COMPANY (US) | 1995-11-22 | — | — | EP | claimed |
| EP-0271260-B1 | Supersensitization of silver halide emulsions | MINNESOTA MINING & MFG (US) | 1995-01-04 | — | — | EP | claimed |
| US-4889796-A | CONTAINING BENZOXAZOLE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1989-12-26 | — | — | US | claimed |
| US-4873184-A | ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-10-10 | — | — | US | claimed |
| EP-0271260-A2 | Supersensitization of silver halide emulsions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-06-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018043-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | MAP3K1, MAP3K11, MAP3K5 | NPC1 1624/4885RAB9A 1848/4885TDP1 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.