⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757682 | 1.00 | — | — | |
| SCHEMBL14731300 | 0.84 | — | — | |
| SCHEMBL4578719 | 0.84 | — | — | |
| SCHEMBL12564801 | 0.81 | ALDH1A1 (0.50) | — | |
| SCHEMBL7356952 | 0.77 | — | — | |
| SCHEMBL87711 | 0.77 | — | — | |
| SCHEMBL523957 | 0.77 | — | — | |
| SCHEMBL2281276 | 0.77 | — | — | |
| SCHEMBL3954454 | 0.77 | — | — | |
| SCHEMBL523804 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423070-A1 | BENZO[H]QUINAZOLINE-4-AMINE DERIVATIVES FOR THE TREATMENT OF CANCER | Redona Therapeutics, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118541354-A | Benzo [ h ] quinazolin-4-amine derivatives for the treatment of cancer | 雷多纳治疗公司 | 2024-08-23 | — | — | CN | disclosed |
| WO-2023196629-A1 | BENZO[H]QUINAZOLINE-4-AMINE DERIVATIVES FOR THE TREATMENT OF CANCER | Redona Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023072913-A1 | BENZO[H]QUINAZOLINE-4-AMINE DERIVATIVES FOR THE TREATMENT OF CANCER | TWENTYEIGHT-SEVEN, INC. (US) | 2023-05-04 | — | — | WO | disclosed |