Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102560 | 0.93 | EGFR (0.48) | EGFREPHA2EPHB4KITKDR | |
| SCHEMBL26100162 | 0.93 | MAPK7 (0.48) | MAPK7ACHEBACE1EGFRPIK3CD | |
| SCHEMBL26101314 | 0.92 | KIT (0.42) | MAPK7EGFREPHA2EPHB4KIT | |
| SCHEMBL26103289 | 0.90 | KIT (0.43) | EGFREPHA2EPHB4KITKDR | |
| SCHEMBL26103479 | 0.89 | EGFR (0.44) | MAPK7EGFRKITKDRP2RX7 | |
| SCHEMBL26102638 | 0.87 | KDR (0.41) | MAPK7EGFREPHA2EPHB4KIT | |
| SCHEMBL30394062 | 0.86 | EGFR (0.49) | MAPK7EGFREPHA2EPHB4KIT | |
| SCHEMBL26101933 | 0.86 | EGFR (0.49) | MAPK7EGFREPHA2EPHB4KIT | |
| SCHEMBL30891778 | 0.84 | MAPK7 (0.45) | MAPK7EGFREPHA2EPHB4KIT | |
| SCHEMBL26099862 | 0.84 | MAPK7 (0.45) | MAPK7EGFREPHA2EPHB4KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |