Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15804474 | 0.84 | NR1H2 (0.60) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL10293026 | 0.81 | NR1H2 (0.60) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL21063626 | 0.80 | NR1H2 (0.58) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL21063507 | 0.79 | NR1H2 (0.54) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL14256078 | 0.78 | NR1H2 (0.61) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL447929 | 0.78 | NR1H2 (0.60) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL72498 | 0.78 | NR1H2 (0.75) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL1193811 | 0.76 | NR1H2 (0.58) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL4932254 | 0.76 | NR1H2 (0.58) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E | |
| SCHEMBL344307 | 0.76 | NR1H2 (0.58) | NR1H2NAMPTUSP2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023071998-A1 | NOVEL PYRIDO OR TRIAZINE-SUBSTITUTED PYRIDO HETEROCYCLIC COMPOUND | 杭州德睿智药科技有限公司 | 2023-05-04 | — | — | WO | disclosed |