SCHEMBL344307

SCHEMBL344307

CC(C)(C)OC(=O)N1CC(CN)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.58
NAMPT P43490 1/20 0.48
USP2 O75604 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
DDB1 Q16531 1/20 0.42
CRBN Q96SW2 1/20 0.42
HPGD P15428 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
RECQL P46063 1/20 0.40
EPHX1 P07099 1/20 0.40
KDM4E B2RXH2 1/20 0.39
PKM P14618 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
RORC P51449 1/20 0.38
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2527213 0.98 NR1H2 (0.57) NR1H2NAMPTUSP2SMN1; SMN2DDB1
Ammonia Solution, Strong SCHEMBL21723640 0.98 NR1H2 (0.57) NR1H2NAMPTUSP2SMN1; SMN2DDB1
SCHEMBL20936863 0.86 NR1H2 (0.74) NR1H2NAMPTUSP2SMN1; SMN2DDB1
SCHEMBL12323778 0.86 NR1H2 (0.74) NR1H2NAMPTUSP2SMN1; SMN2DDB1
SCHEMBL29501587 0.86 NR1H2 (0.74) NR1H2NAMPTUSP2SMN1; SMN2DDB1
SCHEMBL3760597 0.86 NR1H2 (0.74) NR1H2NAMPTUSP2SMN1; SMN2DDB1
SCHEMBL321665 0.86 NR1H2 (0.49) NR1H2USP2SMN1; SMN2HPGDMEN1
SCHEMBL6197 0.86 NR1H2 (0.49) NR1H2USP2SMN1; SMN2HPGDMEN1
SCHEMBL346504 0.86 NR1H2 (0.49) NR1H2USP2SMN1; SMN2HPGDMEN1
SCHEMBL14743842 0.86 NR1H2 (0.55) NR1H2NAMPTUSP2SMN1; SMN2DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099594-A1 THERAPEUTIC BIFUNCTIONAL AGENTS INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2026-05-15 WO disclosed
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS REMEDY PLAN, INC. (US) 2026-05-07 US disclosed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-02 US disclosed
US-20260083708-A1 IL-17 MODULATORS AND USES THEREOF NNOCARE PHARMA INC (US) 2026-03-26 US disclosed
US-12582661-B2 Synthesis and application of class of respiratory syncytial virus inhibitors Shanghai Ark Biopharmaceutical Co., Ltd. (CN) 2026-03-24 US disclosed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
EP-4436667-B1 PIPERAZINYLSULFONYLARYL COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS HOFFMANN LA ROCHE (CH) 2026-01-21 EP disclosed
US-12528781-B2 Heterocyclic GLP-1 agonists GASHERBRUM BIO, INC. (US) 2026-01-20 US disclosed
WO-2005056003-A1 DPP-IV INHIBITORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2005-06-23 WO disclosed
WO-2005056003-A1 DPP-IV INHIBITORS SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) 2005-06-23 WO disclosed
WO-2005042540-A1 THIENO-PYRIDINONE DERIVATIVES AS KINASE INHIBITORS CELLTECH R & D LIMITED (GB) 2005-05-12 WO disclosed
US-20050059702-A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy ANORMED CORPORATION (CA) 2005-03-17 US disclosed
WO-2004093817-A2 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY ANORMED INC. (CA) 2004-11-04 WO disclosed
WO-2004091518-A2 CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS ANORMED INC. (CA) 2004-10-28 WO disclosed
US-20040209921-A1 CXCR4 chemokine receptor binding comounds ANORMED CORPORATION (CA) 2004-10-21 US disclosed
EP-1456200-A1 LACTAMS AS TACHYKININ ANTAGONISTS Pfizer Limited (GB) 2004-09-15 EP disclosed
US-20040132710-A1 Lactams as tachkinin antagonists PFIZER INC. 2004-07-08 US disclosed
WO-2003051868-A1 LACTAMS AS TACHYKININ ANTAGONISTS PFIZER LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040132710-A1 Lactams as tachkinin antagonists PROKR1, TACR2, TACR1 NR1H2 1184/4885NAMPT 1880/4885USP2 3673/4885
US-20260083708-A1 IL-17 MODULATORS AND USES THEREOF IL17A, IL2, IL23R NR1H2 51/4885NAMPT 3713/4885USP2 4339/4885
US-12528781-B2 Heterocyclic GLP-1 agonists GLP1R, GIPR, VIP NR1H2 3555/4885NAMPT 2745/4885USP2 3639/4885
US-20260092057-A1 BCL-XL/BCL-2 DEGRADERS AND USES THEREOF BCL2L2, BCL2A1, BCL2L1 NR1H2 2155/4885NAMPT 4321/4885USP2 1066/4885
US-20260125367-A1 CANCER TREATMENTS TARGETING CANCER STEM CELLS MCL1, MALT1, BCL6 NR1H2 164/4885NAMPT 3339/4885USP2 2512/4885
US-20040209921-A1 CXCR4 chemokine receptor binding comounds CXCR4, CXCR1, CXCR3 NR1H2 105/4885NAMPT 2649/4885USP2 4210/4885
US-20050059702-A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy CXCR4, CXCR1, CCR5 NR1H2 116/4885NAMPT 1200/4885USP2 3512/4885
US-12582661-B2 Synthesis and application of class of respiratory syncytial virus inhibitors SNU13, TMPRSS11D, SPTBN1 NR1H2 2971/4885NAMPT 1825/4885USP2 4536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.