Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 13/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.43 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | BLK | P51451 | 1/20 | 0.43 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.43 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273240 | 1.00 | CAMK1D (0.46) | CAMK1DTIPARPMAP3K7CSF1RPIM1 | |
| SCHEMBL25273241 | 1.00 | CAMK1D (0.46) | CAMK1DTIPARPMAP3K7CSF1RPIM1 | |
| SCHEMBL29271180 | 0.84 | PARP1 (0.41) | TIPARPCHRM2CHRM1GPR119 | |
| SCHEMBL29271206 | 0.84 | PARP1 (0.41) | TIPARPCHRM2CHRM1GPR119 | |
| SCHEMBL25223829 | 0.82 | CHRM2 (0.44) | TIPARPSYKCHRM2CHRM1 | |
| SCHEMBL25273846 | 0.82 | CHRM2 (0.44) | TIPARPSYKCHRM2CHRM1 | |
| SCHEMBL25225065 | 0.79 | POLB (0.49) | TIPARPCHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL31381862 | 0.78 | POLB (0.48) | TIPARPCHRM2CHRM1 | |
| SCHEMBL25700042 | 0.78 | CA1 (0.49) | SYKCHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL31381926 | 0.77 | LMNA (0.47) | TIPARPCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076983-A1 | PYRIDIZIN-3(2H)-ONE DERIVATIVES | GILEAD SCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |