Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395126 | 1.00 | KIT (0.51) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL26100883 | 0.92 | KIT (0.51) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL26101038 | 0.89 | RAF1 (0.48) | KITKDREGFRPDGFRBPDGFRA | |
| SCHEMBL26101812 | 0.86 | EGFR (0.52) | KITKDREGFRPDGFRBPDGFRA | |
| SCHEMBL26535219 | 0.85 | KIT (0.50) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL30394404 | 0.84 | AURKA (0.47) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL26536066 | 0.84 | AURKA (0.47) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL26103044 | 0.84 | AURKA (0.47) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL26103561 | 0.84 | EGFR (0.45) | KITKDREGFRPDGFRBAURKA | |
| SCHEMBL29238270 | 0.80 | AURKA (0.46) | KITKDREGFRPDGFRBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201909-A | Quinazoline derivative compound and use thereof | 株式会社沃若诺伊 | 2024-06-14 | — | — | CN | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |