Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 12/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26463109 | 0.87 | CYP17A1 (0.46) | CYP17A1CYP1A2LCKBTKATM | |
| SCHEMBL12811651 | 0.85 | CYP1A2 (0.51) | CYP17A1CYP1A2MAOAMAOBCYP3A4 | |
| SCHEMBL26463116 | 0.84 | CYP17A1 (0.43) | CYP17A1CYP1A2LCKBTK | |
| SCHEMBL26462973 | 0.84 | CYP17A1 (0.47) | CYP17A1CYP1A2LCKBTK | |
| SCHEMBL29988790 | 0.82 | TDO2 (0.49) | CYP17A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3421743 | 0.82 | TDO2 (0.49) | CYP17A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12023184 | 0.81 | IDO1 (0.48) | IDO1MAOAMAOBMAPTHPGD | |
| SCHEMBL21128380 | 0.78 | CYP17A1 (0.50) | CYP17A1CYP1A2LCKBTKCYP3A4 | |
| SCHEMBL3954316 | 0.78 | IDO1 (0.43) | CYP17A1IDO1MAOAMAOBMAPT | |
| SCHEMBL758202 | 0.78 | HPGD (0.52) | CYP1A2MAPTHPGDNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072026-A1 | SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-05-04 | — | — | WO | disclosed |