Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 16/20 | 0.41 |
| ▸ | BLK | P51451 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582523 | 1.00 | ITK (0.43) | ITKBTKBLKFGFR1FGFR4 | |
| SCHEMBL30582525 | 0.97 | ITK (0.44) | ITKBTKBLK | |
| SCHEMBL30582513 | 0.97 | ITK (0.44) | ITKBTKBLK | |
| SCHEMBL30582574 | 0.94 | ITK (0.40) | ITKBTKBLKFGFR1FGFR4 | |
| SCHEMBL30582508 | 0.91 | ITK (0.48) | ITKBTKFGFR1FGFR4 | |
| SCHEMBL26587732 | 0.91 | BTK (0.44) | ITKBTKFGFR1FGFR4EGFR | |
| SCHEMBL30582518 | 0.89 | ITK (0.40) | ITKBTKBLKFGFR1FGFR4 | |
| SCHEMBL30582594 | 0.88 | SRC (0.41) | EGFR | |
| SCHEMBL26107396 | 0.88 | SRC (0.41) | EGFR | |
| SCHEMBL31219342 | 0.88 | ITK (0.40) | ITKBTKFGFR1FGFR4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | claimed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |