Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 6/20 | 0.39 |
| ▸ | JAK3 | P52333 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 7/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.39 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 3/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26587873 | 0.88 | ITK (0.49) | ITKBTKJAK2JAK3EGFR | |
| SCHEMBL30582523 | 0.88 | ITK (0.43) | ITKBTKJAK2JAK3EGFR | |
| SCHEMBL26104650 | 0.88 | ITK (0.43) | ITKBTKJAK2JAK3EGFR | |
| SCHEMBL30582508 | 0.87 | ITK (0.48) | ITKBTKFGFR2FGFR1FGFR3 | |
| SCHEMBL30582524 | 0.87 | NUDT14 (0.41) | BTKJAK2JAK3EGFRFGFR2 | |
| SCHEMBL31219355 | 0.87 | SRC (0.42) | EGFR | |
| SCHEMBL30582525 | 0.87 | ITK (0.44) | ITKBTKNUDT14 | |
| SCHEMBL30582513 | 0.87 | ITK (0.44) | ITKBTKNUDT14 | |
| SCHEMBL30582528 | 0.86 | BTK (0.38) | ITKBTKJAK2JAK3EGFR | |
| SCHEMBL26587541 | 0.86 | FGFR1 (0.47) | BTKEGFRFGFR2NUDT14FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |