Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582570 | 1.00 | SRC (0.42) | SRCCHEK2EGFRTGFBR1ABL1 | |
| SCHEMBL30582600 | 0.90 | SRC (0.44) | SRCCHEK2EGFRTGFBR1ABL1 | |
| SCHEMBL26104706 | 0.90 | SRC (0.44) | SRCCHEK2EGFRTGFBR1ABL1 | |
| SCHEMBL30582507 | 0.88 | BTK (0.43) | EGFR | |
| SCHEMBL26105815 | 0.85 | LCK (0.37) | SRCKDR | |
| SCHEMBL30582628 | 0.85 | LCK (0.37) | SRCKDR | |
| SCHEMBL26104676 | 0.84 | MAP4K4 (0.38) | SRCEGFRTGFBR1ABL1ABL2 | |
| SCHEMBL30582554 | 0.84 | MAP4K4 (0.38) | SRCEGFRTGFBR1ABL1ABL2 | |
| SCHEMBL26108992 | 0.83 | LCK (0.33) | EGFRRETKDR | |
| SCHEMBL30582647 | 0.83 | SRC (0.41) | SRCEGFRTGFBR1ABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |