Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ABL2 | P42684 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108267 | 1.00 | SRC (0.41) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL30582555 | 0.91 | SRC (0.50) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL26108116 | 0.91 | SRC (0.50) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL30582636 | 0.90 | HDAC2 (0.44) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL26108808 | 0.90 | HDAC2 (0.44) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL30582600 | 0.88 | SRC (0.44) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL26104706 | 0.88 | SRC (0.44) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL30582586 | 0.88 | SRC (0.41) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL26108691 | 0.88 | SRC (0.41) | SRCEGFRABL1ABL2TGFBR1 | |
| SCHEMBL26587704 | 0.88 | FGFR4 (0.44) | EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |