SCHEMBL26106829

SCHEMBL26106829

Cn1c(C2=CCC3(CCNCC3)CC2)c(-c2ncc(C(F)(F)F)cn2)c2c(N)ncnc21

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SOS1 Q07889 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31219432 0.87 RET (0.33) —
SCHEMBL26108241 0.87 LRRK2 (0.39) —
SCHEMBL30582547 0.87 LRRK2 (0.39) —
SCHEMBL26107963 0.87 LRRK2 (0.34) —
SCHEMBL26108491 0.84 — —
SCHEMBL26106237 0.84 DYRK1A (0.33) —
SCHEMBL30582602 0.84 DYRK1A (0.33) —
SCHEMBL26588640 0.84 FGFR1 (0.41) —
SCHEMBL30582567 0.83 SRC (0.36) —
SCHEMBL26105703 0.83 SRC (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4499616-A1 SPIROBICYCLIC COMPOUNDS Acerand Therapeutics (Hong Kong) Limited (HK) 2025-02-05 — — EP disclosed
CN-119013260-A Spirobicyclic compounds 优领医药科技(香港)有限公司 2024-11-22 — — CN disclosed
WO-2024091370-A1 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS ACERAND THERAPEUTICS (USA) LIMITED (US) 2024-05-02 — — WO disclosed
WO-2023192502-A1 SPIROBICYCLIC COMPOUNDS ACERAND THERAPEUTICS (USA) LIMITED (US) 2023-10-05 — — WO disclosed
WO-2023192502-A1 SPIROBICYCLIC COMPOUNDS ACERAND THERAPEUTICS (USA) LIMITED (US) 2023-10-05 — — WO disclosed
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