Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107780 | 1.00 | TRPV1 (0.39) | TRPV1HSD11B1TRPA1RPS6KB1KDM4E | |
| SCHEMBL26106571 | 0.80 | TRPV1 (0.41) | TRPV1HSD11B1TRPA1 | |
| SCHEMBL30591894 | 0.80 | TEAD1 (0.49) | TRPV1TRPA1RPS6KB1AKT1AKT2 | |
| SCHEMBL26107171 | 0.80 | TEAD1 (0.49) | TRPV1TRPA1RPS6KB1AKT1AKT2 | |
| SCHEMBL26110897 | 0.80 | TEAD1 (0.49) | TRPV1TRPA1RPS6KB1AKT1AKT2 | |
| SCHEMBL26106075 | 0.78 | EPHX2 (0.48) | TRPV1 | |
| SCHEMBL30591873 | 0.78 | EPHX2 (0.48) | TRPV1 | |
| SCHEMBL26103628 | 0.77 | CNR2 (0.45) | TRPV1HSD11B1TRPA1KDM4EGAA | |
| SCHEMBL26105650 | 0.77 | PDE10A (0.42) | TRPV1TRPA1 | |
| SCHEMBL26107483 | 0.77 | TRPV1 (0.46) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |