Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106903 | 0.86 | PDE10A (0.42) | TRPV1HSD11B1PDE10ASLC6A7TRPA1 | |
| SCHEMBL26105650 | 0.82 | PDE10A (0.42) | TRPV1PDE10ATRPA1 | |
| SCHEMBL26107483 | 0.82 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL26105942 | 0.81 | SMO (0.41) | TRPV1SMOHSD11B1 | |
| SCHEMBL26103628 | 0.81 | CNR2 (0.45) | TRPV1HSD11B1SLC6A7TRPA1 | |
| SCHEMBL26106984 | 0.80 | TRPV1 (0.39) | TRPV1HSD11B1TRPA1 | |
| SCHEMBL26107780 | 0.80 | TRPV1 (0.39) | TRPV1HSD11B1TRPA1 | |
| SCHEMBL26104579 | 0.79 | MAPT (0.41) | TRPV1 | |
| SCHEMBL26107660 | 0.78 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL30591592 | 0.76 | SLC6A7 (0.48) | TRPV1SLC6A7TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | claimed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |