Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 9/20 | 0.39 |
| ▸ | BCR | P11274 | 7/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26103974 | 0.87 | TRPV1 (0.33) | DHODHTRPV1ABL1KIT | |
| SCHEMBL26105442 | 0.86 | PDE10A (0.34) | TRPV1 | |
| SCHEMBL26107483 | 0.86 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL26106402 | 0.85 | NPSR1 (0.41) | KITALDH1A1MAPT | |
| SCHEMBL26107437 | 0.84 | DHODH (0.38) | DHODHTRPV1LMNAKDM4EALDH1A1 | |
| SCHEMBL26105644 | 0.83 | PDE10A (0.41) | TRPV1 | |
| SCHEMBL26104535 | 0.82 | TRPV1 (0.43) | DHODHTRPV1LMNARAB9A | |
| SCHEMBL30591801 | 0.80 | TRPV1 (0.50) | DHODHTRPV1ABL1BCREPHX2 | |
| SCHEMBL26108742 | 0.80 | TRPV1 (0.50) | DHODHTRPV1ABL1BCREPHX2 | |
| SCHEMBL26106597 | 0.79 | TRPV1 (0.33) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |