Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105650 | 0.90 | PDE10A (0.42) | PDE10ATRPV1 | |
| SCHEMBL26107722 | 0.85 | HRH4 (0.44) | PDE10A | |
| SCHEMBL26106840 | 0.84 | PDE10A (0.41) | PDE10A | |
| SCHEMBL26103135 | 0.84 | PDE10A (0.41) | PDE10ATRPV1 | |
| SCHEMBL26108503 | 0.84 | PDE10A (0.37) | PDE10ATRPV1 | |
| SCHEMBL26107346 | 0.83 | DHODH (0.44) | TRPV1 | |
| SCHEMBL26108261 | 0.82 | PDE10A (0.35) | PDE10A | |
| SCHEMBL26135830 | 0.78 | BTK (0.45) | PDE10ATRPV1 | |
| SCHEMBL30591705 | 0.78 | BTK (0.45) | PDE10ATRPV1 | |
| SCHEMBL26104579 | 0.78 | MAPT (0.41) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |