Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107166 | 0.87 | PDE10A (0.41) | PDE10A | |
| SCHEMBL26104202 | 0.85 | SCN9A (0.38) | SCN9APDE10AALOX5APFEN1SCN10A | |
| SCHEMBL26112177 | 0.85 | PDE10A (0.37) | SCN9APDE10AALOX5APFEN1SCN10A | |
| SCHEMBL26107399 | 0.83 | SCN9A (0.38) | SCN9APDE10ASCN10ALIPE | |
| SCHEMBL26106268 | 0.81 | SCN9A (0.39) | SCN9ASCN10ALIPE | |
| SCHEMBL26103613 | 0.81 | SCN9A (0.39) | SCN9ASCN10ALIPE | |
| SCHEMBL26109504 | 0.80 | SCN9A (0.41) | SCN9ASCN10ALIPE | |
| SCHEMBL30591731 | 0.80 | SCN9A (0.41) | SCN9ASCN10ALIPE | |
| SCHEMBL30591657 | 0.80 | SCN9A (0.41) | SCN9AALOX5APFEN1SCN10ALIPE | |
| SCHEMBL26107706 | 0.80 | SCN9A (0.41) | SCN9AALOX5APFEN1SCN10ALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | claimed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |