Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105746 | 0.90 | PDE10A (0.38) | SCN9APDE10ASCN10ALIPE | |
| SCHEMBL26106268 | 0.89 | SCN9A (0.39) | SCN9ASCN10ALIPE | |
| SCHEMBL26103613 | 0.88 | SCN9A (0.39) | SCN9ASCN10ALIPE | |
| SCHEMBL26108191 | 0.87 | PDE10A (0.36) | PDE10A | |
| SCHEMBL26107318 | 0.87 | SCN9A (0.37) | SCN9ASCN10ALIPE | |
| SCHEMBL26107166 | 0.87 | PDE10A (0.41) | PDE10A | |
| SCHEMBL31474452 | 0.85 | PDE10A (0.41) | SCN9APDE10ASCN10ALIPE | |
| SCHEMBL26107789 | 0.84 | SCN9A (0.35) | SCN9APDE10ALIPE | |
| SCHEMBL26107684 | 0.83 | SCN9A (0.37) | SCN9APDE10ASCN10ALIPE | |
| SCHEMBL26105333 | 0.82 | PDE10A (0.37) | SCN9APDE10ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |