Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 7/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | ABL2 | P42684 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109846 | 0.92 | KCNH2 (0.36) | EGFRKDRTEKBTKBLK | |
| SCHEMBL26109317 | 0.91 | SRC (0.41) | SRCEGFRKDRABL1ABL2 | |
| SCHEMBL26105801 | 0.91 | PTPN11 (0.35) | EGFRKDRFGFR2TEKBTK | |
| SCHEMBL26108781 | 0.90 | BTK (0.35) | EGFRKDRRIPK2FGFR2TEK | |
| SCHEMBL26109060 | 0.90 | BTK (0.35) | EGFRKDRTEKBTKBLK | |
| SCHEMBL26107996 | 0.90 | ITK (0.35) | PIK3CDBTKITKRET | |
| SCHEMBL26106100 | 0.89 | — | — | |
| SCHEMBL26106955 | 0.89 | ADORA2A (0.38) | SRCEGFRKDRTEKFLT3 | |
| SCHEMBL26109353 | 0.87 | RET (0.32) | SRCEGFRKDRABL1PIK3CD | |
| SCHEMBL26107761 | 0.86 | BTK (0.35) | EGFRKDRTEKBTKBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |