Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109006 | 0.91 | RIPK2 (0.35) | FGFR1FGFR2FGFR4FGFR3LRRK2 | |
| SCHEMBL26108002 | 0.90 | SRC (0.37) | BTKFGFR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL26105801 | 0.89 | PTPN11 (0.35) | BTKFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26109178 | 0.89 | FGFR1 (0.31) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26107398 | 0.89 | — | — | |
| SCHEMBL26109353 | 0.88 | RET (0.32) | LRRK2EGFRKDR | |
| SCHEMBL26109846 | 0.88 | KCNH2 (0.36) | BTKEGFRKDRTEKPTPN11 | |
| SCHEMBL26106008 | 0.87 | ITK (0.35) | FGFR1FGFR2FGFR4FGFR3LRRK2 | |
| SCHEMBL26108120 | 0.87 | LRRK2 (0.32) | FGFR1FGFR2FGFR4FGFR3LRRK2 | |
| SCHEMBL26107996 | 0.87 | ITK (0.35) | BTKLRRK2RPS6KB1KITPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |