Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.40 |
| ▸ | KDR | P35968 | 11/20 | 0.40 |
| ▸ | TEK | Q02763 | 11/20 | 0.40 |
| ▸ | BTK | Q06187 | 10/20 | 0.39 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.37 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | ITK | Q08881 | 2/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26113306 | 0.87 | BTK (0.40) | LCKKDRTEKBTKBLK | |
| SCHEMBL30582627 | 0.84 | BTK (0.49) | LCKKDRBTKNUDT14NUDT5 | |
| SCHEMBL26109125 | 0.84 | LCK (0.44) | LCKKDRTEKBTKNUDT14 | |
| SCHEMBL26109060 | 0.82 | BTK (0.35) | LCKKDRTEKBTKNUDT14 | |
| SCHEMBL26107761 | 0.80 | BTK (0.35) | LCKKDRTEKBTKNUDT14 | |
| SCHEMBL26587238 | 0.79 | LCK (0.49) | LCKKDRTEKBTKNUDT14 | |
| SCHEMBL22676631 | 0.77 | BTK (0.53) | LCKKDRBTKNUDT14NUDT5 | |
| SCHEMBL26108768 | 0.77 | BTK (0.36) | LCKKDRTEKBTKNUDT14 | |
| SCHEMBL30582591 | 0.76 | LCK (0.42) | LCKKDRTEKBTKNUDT14 | |
| SCHEMBL26108281 | 0.76 | LCK (0.42) | LCKKDRTEKBTKNUDT14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |