Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.42 |
| ▸ | TEK | Q02763 | 13/20 | 0.42 |
| ▸ | KDR | P35968 | 12/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.39 |
| ▸ | BTK | Q06187 | 7/20 | 0.39 |
| ▸ | NUDT14 | O95848 | 2/20 | 0.38 |
| ▸ | NUDT5 | Q9UKK9 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | CSK | P41240 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582591 | 1.00 | LCK (0.42) | LCKTEKKDRSRCBTK | |
| SCHEMBL26587238 | 0.86 | LCK (0.49) | LCKTEKKDRSRCBTK | |
| SCHEMBL26109125 | 0.85 | LCK (0.44) | LCKTEKKDRSRCBTK | |
| SCHEMBL29407686 | 0.84 | LCK (0.49) | LCKTEKKDRSRCBTK | |
| SCHEMBL22659188 | 0.84 | LCK (0.49) | LCKTEKKDRSRCBTK | |
| SCHEMBL26113306 | 0.83 | BTK (0.40) | LCKTEKKDRBTKEGFR | |
| SCHEMBL30582500 | 0.83 | BTK (0.55) | BTKEGFRERBB2RETFLT3 | |
| SCHEMBL26105238 | 0.82 | SRC (0.43) | LCKTEKKDRSRCBTK | |
| SCHEMBL30582582 | 0.82 | SRC (0.43) | LCKTEKKDRSRCBTK | |
| SCHEMBL31219400 | 0.80 | LCK (0.42) | LCKTEKKDRSRCBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |