Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 16/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108220 | 1.00 | IRAK4 (0.41) | IRAK4ABL1L3MBTL1LMNA | |
| SCHEMBL26108414 | 0.89 | L3MBTL1 (0.40) | IRAK4ABL1L3MBTL1LMNA | |
| SCHEMBL26108421 | 0.89 | L3MBTL1 (0.40) | IRAK4ABL1L3MBTL1LMNA | |
| SCHEMBL30569017 | 0.86 | BTK (0.40) | IRAK4 | |
| SCHEMBL25143665 | 0.86 | IRAK4 (0.41) | IRAK4ABL1L3MBTL1LMNA | |
| SCHEMBL30201649 | 0.86 | IRAK4 (0.41) | IRAK4ABL1L3MBTL1LMNA | |
| SCHEMBL26111654 | 0.85 | L3MBTL1 (0.40) | IRAK4ABL1L3MBTL1LMNA | |
| SCHEMBL31436648 | 0.83 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL26598787 | 0.83 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL26107977 | 0.82 | KDM4E (0.39) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186069-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 石药集团中奇制药技术（石家庄）有限公司 | 2023-10-05 | — | — | WO | disclosed |