Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31202607 | 1.00 | MEN1 (0.41) | MEN1ALOX15MAPK1KMT2ATEAD1 | |
| SCHEMBL26107184 | 0.89 | TEAD1 (0.39) | MEN1ALOX15MAPK1KMT2ATEAD1 | |
| SCHEMBL31202705 | 0.89 | TEAD1 (0.39) | MEN1ALOX15MAPK1KMT2ATEAD1 | |
| SCHEMBL31202803 | 0.87 | PTGS2 (0.51) | SCN9APTGS2CYP2C9PDPK1PTGS1 | |
| SCHEMBL26108786 | 0.87 | PTGS2 (0.51) | SCN9APTGS2CYP2C9PDPK1PTGS1 | |
| SCHEMBL31202718 | 0.85 | CYP2C9 (0.42) | SCN9APTGS2CYP2C9PDPK1RORC | |
| SCHEMBL26107647 | 0.85 | CYP2C9 (0.42) | SCN9APTGS2CYP2C9PDPK1RORC | |
| SCHEMBL30602812 | 0.84 | PTGS2 (0.43) | TEAD1YAP1SCN9APTGS2CYP2C9 | |
| SCHEMBL31202723 | 0.84 | NPY5R (0.45) | TEAD1YAP1SCN9APTGS2CYP2C9 | |
| SCHEMBL26105623 | 0.84 | NPY5R (0.45) | TEAD1YAP1SCN9APTGS2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186058-A1 | INDAZOLE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2023-10-05 | — | — | WO | disclosed |