Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 4/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30591799 | 1.00 | SCN9A (0.42) | SCN9ALIPEPDE10ATEAD1TRPC6 | |
| SCHEMBL30591893 | 0.88 | SCN9A (0.43) | SCN9ALIPETEAD1TRPC6TEAD3 | |
| SCHEMBL26106689 | 0.88 | SCN9A (0.43) | SCN9ALIPETEAD1TRPC6TEAD3 | |
| SCHEMBL26103340 | 0.87 | TEAD1 (0.39) | PDE10ATEAD1TEAD3 | |
| SCHEMBL30591679 | 0.87 | TEAD1 (0.39) | PDE10ATEAD1TEAD3 | |
| SCHEMBL26106644 | 0.87 | LIPE (0.42) | SCN9ALIPETEAD1TRPC6TEAD3 | |
| SCHEMBL26108993 | 0.87 | PDE10A (0.42) | SCN9ALIPEPDE10AFGFR4 | |
| SCHEMBL30591823 | 0.86 | SCN9A (0.42) | SCN9ALIPEPDE10ATRPC6 | |
| SCHEMBL26108593 | 0.86 | SCN9A (0.42) | SCN9ALIPEPDE10ATRPC6 | |
| SCHEMBL30591842 | 0.85 | SCN9A (0.42) | SCN9ALIPEPDE10ATRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | claimed |