Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582636 | 1.00 | HDAC2 (0.44) | HDAC2HDAC1SRCEGFRMEN1 | |
| SCHEMBL30582555 | 0.92 | SRC (0.50) | SRCEGFRTGFBR1MAP4K4RET | |
| SCHEMBL26108116 | 0.92 | SRC (0.50) | SRCEGFRTGFBR1MAP4K4RET | |
| SCHEMBL26107804 | 0.91 | SRC (0.42) | HDAC2HDAC1SRCEGFRTGFBR1 | |
| SCHEMBL30582630 | 0.91 | SRC (0.42) | HDAC2HDAC1SRCEGFRTGFBR1 | |
| SCHEMBL30582647 | 0.90 | SRC (0.41) | HDAC2HDAC1SRCEGFRTGFBR1 | |
| SCHEMBL26108267 | 0.90 | SRC (0.41) | HDAC2HDAC1SRCEGFRTGFBR1 | |
| SCHEMBL30582607 | 0.89 | HDAC2 (0.39) | HDAC2HDAC1SRCEGFRTGFBR1 | |
| SCHEMBL26106956 | 0.89 | HDAC2 (0.39) | HDAC2HDAC1SRCEGFRTGFBR1 | |
| SCHEMBL30582600 | 0.89 | SRC (0.44) | SRCEGFRTGFBR1RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |