SCHEMBL26108977

SCHEMBL26108977

COC(=O)OC1C(CO[Si](C)(C)C(C)(C)C)OC(n2cnc3c(NC(=O)c4ccccc4)ncnc32)C1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRMT6 Q96LA8 1/20 0.52
▸ PRKAB2 O43741 1/20 0.44
▸ PRKAG1 P54619 1/20 0.44
▸ PRKAA2 P54646 1/20 0.44
▸ PRKAA1 Q13131 1/20 0.44
▸ PRKAG3 Q9UGI9 1/20 0.44
▸ PRKAG2 Q9UGJ0 1/20 0.44
▸ PRKAB1 Q9Y478 1/20 0.44
▸ P2RY12 Q9H244 5/20 0.44
▸ P2RX3 P56373 1/20 0.44
▸ P2RX4 Q99571 1/20 0.44
▸ P2RX2 Q9UBL9 1/20 0.44
▸ P2RY2 P41231 1/20 0.42
▸ P2RY1 P47900 1/20 0.42
▸ P2RY6 Q15077 1/20 0.42
▸ BMPR1B O00238 1/20 0.42
▸ DNPH1 O43598 2/20 0.41
▸ ADORA1 P30542 2/20 0.41
▸ ADORA3 P0DMS8 1/20 0.41
▸ ADORA2A P29274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26108971 1.00 PRMT6 (0.52) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL22206844 0.94 PRMT6 (0.50) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL30586895 0.93 PRMT6 (0.57) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26112399 0.93 PRMT6 (0.48) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26107621 0.93 PRMT6 (0.53) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26107628 0.93 PRMT6 (0.53) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26109827 0.92 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26109806 0.91 PRMT6 (0.47) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26109690 0.90 PRMT6 (0.48) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1
SCHEMBL26109696 0.90 PRMT6 (0.48) PRMT6PRKAB2PRKAG1PRKAA2PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 — — WO disclosed
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