⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264560 | 1.00 | — | — | |
| SCHEMBL7607018 | 1.00 | — | — | |
| SCHEMBL282573 | 1.00 | — | — | |
| SCHEMBL354898 | 1.00 | — | — | |
| SCHEMBL354899 | 1.00 | — | — | |
| SCHEMBL264287 | 1.00 | — | — | |
| SCHEMBL283428 | 1.00 | — | — | |
| Propanol SCHEMBL28037772 | 0.91 | CYP2A6 (0.32) | — | |
| SCHEMBL28037795 | 0.85 | TDP1 (0.39) | — | |
| SCHEMBL17881257 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083577-A1 | SULFONATES OF FURAN-2,5-DIMETHANOL AND (TETRAHYDROFURAN-2,5-DIYL)DIMETHANOL AND DERIVATIVES THEREOF | Archer Daniels Midland Company (US) | 2016-10-26 | — | — | EP | claimed |
| WO-2015094965-A1 | SULFONATES OF FURAN-2,5-DIMETHANOL AND (TETRAHYDROFURAN-2,5-DIYL)DIMETHANOL AND DERIVATIVES THEREOF | ARCHER DANIELS MIDLAND COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| WO-2023147161-A2 | NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF | New Frontier Bio, Inc. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023020640-A1 | 7-SUBSTITUTED 7-DEAZAADENINE-CONTAINING 2',3'-CYCLIC DINUCLEOTIDES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V. V. I. (CZ) | 2023-02-23 | — | — | WO | disclosed |
| WO-2021188959-A1 | PRODRUGS OF 4'-C-SUBSTITUTED-2-HALO-2'-DEOXYADENOSINE NUCLEOSIDES AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2020138336-A1 | MUTATED TRNA FOR CODON EXPANSION | 中外製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |
| WO-2017075477-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING \"STIMULATOR OF INTERFERON GENE\"-DEPENDENT SIGNALLING | Aduro Biotech, Inc. (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017053216-A2 | 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS AND PREPARATIONS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017027646-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS AS STING AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-02-16 | — | — | WO | disclosed |
| US-20170044205-A1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES NUCLEOTIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. | 2017-02-16 | — | — | US | disclosed |
| US-7514410-B2 | Hepatitis C therapies | BIOCRYST PHARMACEUTICALS, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20090012252-A1 | Polymeric Derivative of Cytidine Metabolic Antagonist | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-01-08 | — | — | US | disclosed |
| US-20090012252-A1 | Polymeric Derivative of Cytidine Metabolic Antagonist | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-01-08 | — | — | US | disclosed |
| US-20080300200-A1 | Therapeutic Furopyrimidines and Thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-20080300200-A1 | Therapeutic Furopyrimidines and Thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-12-04 | — | — | US | disclosed |
| US-7429571-B2 | Therapeutic furopyrimidines and thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| US-7429571-B2 | Therapeutic furopyrimidines and thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| WO-2008089105-A2 | ANTIVIRAL NUCLEOSIDE ANALOGS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| EP-1881020-A1 | POLYMERIC DERIVATIVE OF CYTIDINE METABOLIC ANTAGONIST | Nippon Kayaku Kabushiki Kaisha (JP) | 2008-01-23 | — | — | EP | disclosed |