⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264560 | 1.00 | — | — | |
| SCHEMBL2610981 | 1.00 | — | — | |
| SCHEMBL282573 | 1.00 | — | — | |
| SCHEMBL354898 | 1.00 | — | — | |
| SCHEMBL354899 | 1.00 | — | — | |
| SCHEMBL264287 | 1.00 | — | — | |
| SCHEMBL283428 | 1.00 | — | — | |
| Propanol SCHEMBL28037772 | 0.91 | CYP2A6 (0.32) | — | |
| SCHEMBL28037795 | 0.85 | TDP1 (0.39) | — | |
| SCHEMBL17881257 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017053216-A2 | 4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS AND PREPARATIONS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2017-03-30 | — | — | WO | disclosed |
| EP-2859008-B1 | MODIFIED OLIGONUCLEOTIDES COMPRISING THIOL FUNCTIONS AND THE USE OF SAME FOR THE DETECTION OF NUCLEIC ACIDS | ETABLISSEMENT FRANÇAIS DU SANG (EFS) (FR) | 2017-02-22 | — | — | EP | disclosed |
| US-9173892-B2 | Acadesine derivatives, products and compositions including same, therapeutic uses thereof, and methods for synthesizing same | UNIVERSITE NICE SOPHIA ANTIPOLIS (FR) | 2015-11-03 | — | — | US | disclosed |
| US-20130018013-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-01-17 | — | — | US | disclosed |
| US-20120122811-A1 | BICYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-05-17 | — | — | US | disclosed |
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-7884202-B2 | Nucleobases are perfluoroalkylated in a one step process with a perfluoroalkyl halide in the presence of a sulfoxide, a peroxide and an iron compound; useful as medicinal drugs, intermediates for medicinal drugs and agricultural chemicals | TOSOH CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20090124796-A1 | Nucleobase Having Perfluoroalkyl Group and Process for Producing the Same | TOSOH CORPORATION (JP) | 2009-05-14 | — | — | US | disclosed |
| US-20090004138-A1 | Bicyclic Nucleosides and Nucleotides as Therapeutic Agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2009-01-01 | — | — | US | disclosed |