Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26105475 | 0.90 | LRRK2 (0.32) | — | |
| SCHEMBL26107398 | 0.85 | — | — | |
| SCHEMBL26107393 | 0.85 | LRRK2 (0.31) | — | |
| SCHEMBL26107075 | 0.84 | RET (0.32) | — | |
| SCHEMBL26108735 | 0.84 | RET (0.31) | — | |
| SCHEMBL30582535 | 0.84 | JAK2 (0.36) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL26106100 | 0.83 | — | — | |
| SCHEMBL26108120 | 0.83 | LRRK2 (0.32) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26108781 | 0.83 | BTK (0.35) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL26109353 | 0.83 | RET (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | claimed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |