Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 10/20 | 0.71 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30593620 | 1.00 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL26568771 | 0.95 | ALDH1A1 (0.79) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL26110509 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL30593621 | 0.84 | KDM4E (0.77) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL26569399 | 0.84 | KDM4E (0.58) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL26112800 | 0.84 | KDM4E (0.77) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL30593623 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL26112639 | 0.81 | KDM4E (0.57) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL26116157 | 0.79 | KDM4E (0.75) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL26568017 | 0.79 | KDM4E (0.66) | ALDH1A1KDM4EHPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023182897-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023182897-A1 | INHIBITORS OF INTERACTIONS BETWEEN TRF1-TIN2 OR TRF2-TIN2 TELOMERIC PROTEINS FOR USE IN ANTICANCER THERAPY | Politechnika Gdańska (PL) | 2023-09-28 | — | — | WO | disclosed |