Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31352773 | 1.00 | SRC (0.38) | SRCPARP1ALDH1A1ENPP1RAB9A | |
| SCHEMBL30590825 | 0.85 | SRC (0.52) | SRCPARP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL26112587 | 0.85 | SRC (0.52) | SRCPARP1ALDH1A1RAB9AKDM4E | |
| SCHEMBL30590827 | 0.81 | PARP1 (0.36) | SRCPARP1ALDH1A1PDPK1 | |
| SCHEMBL26112568 | 0.81 | PARP1 (0.36) | SRCPARP1ALDH1A1PDPK1 | |
| SCHEMBL30590804 | 0.77 | PARP1 (0.45) | PARP1ALDH1A1PDPK1CHEK1PIM1 | |
| SCHEMBL26112788 | 0.77 | PARP1 (0.45) | PARP1ALDH1A1PDPK1CHEK1PIM1 | |
| SCHEMBL1011012 | 0.74 | PARP1 (0.50) | SRCPARP1ALDH1A1ENPP1PDPK1 | |
| SCHEMBL26114200 | 0.74 | ENPP1 (0.55) | ALDH1A1ENPP1 | |
| SCHEMBL18655504 | 0.74 | PARP1 (0.50) | SRCPARP1ALDH1A1CHEK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504719-A1 | EGFR INHIBITORS | Blueprint Medicines Corporation (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |