Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590825 | 1.00 | SRC (0.52) | SRCADORA3ALDH1A1PARP1HPGD | |
| SCHEMBL31352773 | 0.85 | SRC (0.38) | SRCADORA3ALDH1A1PARP1HPGD | |
| SCHEMBL26112062 | 0.85 | SRC (0.38) | SRCADORA3ALDH1A1PARP1HPGD | |
| SCHEMBL26112568 | 0.80 | PARP1 (0.36) | SRCALDH1A1PARP1PDPK1MKNK1 | |
| SCHEMBL30590827 | 0.80 | PARP1 (0.36) | SRCALDH1A1PARP1PDPK1MKNK1 | |
| SCHEMBL30590804 | 0.79 | PARP1 (0.45) | ADORA3ALDH1A1PARP1SMN1; SMN2PDPK1 | |
| SCHEMBL26112788 | 0.79 | PARP1 (0.45) | ADORA3ALDH1A1PARP1SMN1; SMN2PDPK1 | |
| SCHEMBL23537901 | 0.72 | ENPP1 (0.50) | SRCADORA3ALDH1A1HPGDKDM4E | |
| SCHEMBL8917 | 0.72 | SRC (0.63) | SRCALDH1A1PARP1KDM4ESMN1; SMN2 | |
| SCHEMBL12247774 | 0.72 | SRC (0.55) | SRCALDH1A1PARP1SMN1; SMN2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080786-A1 | SALT AND SOLID FORMS OF AN EGFR INHIBITOR | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |
| EP-4504719-A1 | EGFR INHIBITORS | Blueprint Medicines Corporation (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |