Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.88 |
| ▸ | CNR2 | P34972 | 3/20 | 0.88 |
| ▸ | FAAH | O00519 | 4/20 | 0.78 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.78 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.75 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.67 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.67 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.67 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.67 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.67 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.67 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.67 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.67 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.67 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.67 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.67 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.67 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.67 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.67 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31659455 | 0.97 | CNR1 (0.92) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7271387 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7264157 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7200728 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7271203 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7199890 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7262778 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7262773 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL10532438 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 | |
| SCHEMBL7268946 | 0.92 | EPHX2 (0.74) | CNR1CNR2FAAHEPHX2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230125-A1 | Small Molecule Allosteric Modulators of Serotonin (5-HT) 5-HT2C and 5-HT2A Receptors | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2025-07-17 | — | — | US | disclosed |
| CN-119677506-A | Small molecule allosteric modulators of serotonin (5-HT) 5-HT2C and 5-HT2A receptors | 得克萨斯系统大学董事会 | 2025-03-21 | — | — | CN | disclosed |
| EP-4504164-A1 | SMALL MOLECULE ALLOSTERIC MODULATORS OF THE SEROTONIN (5-HT) 5-HT2C AND 5-HT2A RECEPTORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023191951-A1 | SMALL MOLECULE ALLOSTERIC MODULATORS OF THE SEROTONIN (5-HT) 5-HT2C AND 5-HT2A RECEPTORS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250230125-A1 | Small Molecule Allosteric Modulators of Serotonin (5-HT) 5-HT2C and 5-HT2A Receptors | HTR2C, HTR2A, HTR5A | CNR1 119/4885CNR2 52/4885FAAH 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.