Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.69 |
| ▸ | SALL4 | Q9UJQ4 | 2/20 | 0.61 |
| ▸ | TRIM33 | Q9UPN9 | 4/20 | 0.60 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2611922 | 0.89 | SALL4 (0.64) | ADORA1ALOX5SALL4TRIM33TRIM24 | |
| SCHEMBL1965729 | 0.88 | ALOX5 (0.72) | ADORA1ALOX5SALL4TRIM33TRIM24 | |
| SCHEMBL2986458 | 0.86 | ALOX5 (0.70) | ADORA1ALOX5SALL4TRIM33TRIM24 | |
| SCHEMBL20889569 | 0.84 | SALL4 (0.67) | ADORA1ALOX5SALL4TRIM33TRIM24 | |
| SCHEMBL2984312 | 0.83 | ALOX5 (0.70) | ADORA1ALOX5SALL4ALDH1A1GAA | |
| SCHEMBL2977991 | 0.83 | ADORA1 (1.00) | ADORA1ALOX5TRIM33TRIM24ALDH1A1 | |
| SCHEMBL15172137 | 0.83 | ADORA1 (0.71) | ADORA1ALOX5SALL4TRIM33TRIM24 | |
| SCHEMBL15172138 | 0.82 | ADORA1 (0.69) | ADORA1ALOX5SALL4TRIM33TRIM24 | |
| SCHEMBL2983996 | 0.81 | ALOX5 (1.00) | ADORA1ALOX5ALDH1A1GAAKDM4E | |
| SCHEMBL1967827 | 0.79 | ADORA1 (0.59) | ADORA1ALOX5SALL4TRIM33TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101122-A1 | IMIDAZO[1,2 A] PYRIDINE 6 CARBOXAMIDE DERIVATIVES, THEIR USE FOR THE TREATMENT OF COLON CANCER AND THEIR METHOD OF MANUFACTURE | UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101122-A1 | IMIDAZO[1,2 A] PYRIDINE 6 CARBOXAMIDE DERIVATIVES, THEIR USE FOR THE TREATMENT OF COLON CANCER AND THEIR METHOD OF MANUFACTURE | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1, CBR1 | ADORA1 714/4885ALOX5 2223/4885SALL4 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.